Advanced tests for skin and respiratory sensitization assessment
نویسندگان
چکیده
منابع مشابه
Advanced tests for skin and respiratory sensitization assessment.
Sens-it-iv is an FP6 Integrated Project that finished in March 2011 after 66 months of activity, thanks to 12 million € of funding. The ultimate goal of the Sens-it-iv project was the development of a set of in vitro methods for the assessment of the skin and respiratory sensitization potential of chemicals and proteins. The level of development was intended to be at the point to enter the pre-...
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این پایان نامه بدنبال بررسی کاربرد ارزیابی مستمر در یک محیط یادگیری زبان دوم از طریق طرح چهار سوال تحقیق زیر بود: (1) درک توانایی های فراگیران زمانیکه که از طریق برآورد عملکرد مستقل آنها امکان پذیر نباشد اما در طول جلسات ارزیابی مستمر مشخص شوند; (2) امکان تقویت توانایی های فراگیران از طریق ارزیابی مستمر; (3) سودمندی ارزیابی مستمر در هدایت آموزش فردی به سمتی که به منطقه ی تقریبی رشد افراد حساس ا...
15 صفحه اولSkin Sensitization in Chemical Risk Assessment
Anne Marie Api Research Institute for Fragrance Materials, Inc. (RIFM), Woodcliff Lake, New Jersey, USA J.H.E. Arts TNO Quality of Life, Zeist, Netherlands Harmonization Project Document No. 5 4 David Basketter Unilever Safety and Environmental Assurance Centre, Sharnbrook, Bedford, United Kingdom Jonathan Chen Antimicrobials Division, Office of Pesticide Programs, Environmental Protection Agen...
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In this paper, we propose a quantitative risk assessment methodology for skin sensitization aiming at the derivation of 'safe' exposure levels for sensitizing chemicals, used e.g., as ingredients in consumer products. Given the limited number of sensitizers tested in human sensitization tests, such as the human repeat-insult patch test (HRIPT) or the human maximization test (HMT), we used EC3 v...
متن کاملSkin irritation and sensitization: mechanisms and new approaches for risk assessment. 1. Skin irritation.
Cutaneous irritation presents a major health problem with serious social and occupational impact. The interaction between an irritant and the human skin depends on multiple factors: the intrinsic properties and the nature of the irritant itself, and specific individual- and environment-related variables. The main pathological mechanisms of irritancy include skin barrier disruption, induction of...
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ژورنال
عنوان ژورنال: ALTEX
سال: 2013
ISSN: 1868-596X
DOI: 10.14573/altex.2013.2.231